Archive for the ‘Healthy Food’ Category

Essential Amino Acid Metabolic Errors: Dangerous and Costly

May 26th, 2010

Making sure our diet has the recommended daily amount of essential amino acids is crucial for good health. However, this does not work for everyone.  For people suffering from essential amino acid metabolic disorders,  normal pathways of essential amino acid metabolism are not functional. This causes a plethora of  mild to severe symptoms that, left untreated, morph into chronic diseases.  Contrary to a simple deficiency, the  cure for  people with essential amino acid metabolic disorders  is more elusive.

So what does an essential amino acid metabolic disorder mean? It means a body has a dysfunctional or a non-functional metabolic pathway for one or more essential amino acids. Ingested essential amino acids cannot be used due to metabolic errors. Imagine gassing up and being unable to start the car due to engine error. Same thing. Body that cannot use ingested essential amino acids and consequently cannot run metabolic processes that depend on them. Unused essential amino acids accumulate in the system in excess concentrations and cause system toxicity, manifesting trough symptoms and diseases.

The problem with amino acid metabolic disorders is that they are notoriously hard to diagnose. On one hand, it takes a detailed lab workup to connect the dots. On the other hand, people are  unaware of the real cause of their health problems. Some cases are even mistaken for a deficiency. Going for supplementation instead of limiting the intake flues the problem rather than solving it,  leading to  hallucinations,  pellagra and excess ammonia levels. And adding oil to the fire is not a good thing.

To get a better picture let’s take a quick look at some essential amino acids disorders:

  • Isoleucine
    • Propionic acidaemia and MSUD – Maple Syrup Urine Disease
  • Leucine
    • Isovaleric acidaemia and MSUD
  • Lysine
    • Hyperlysinaemia
  • Methionine
    • Hypermethioninaemia
  • Phenylalanine
    • Phenylketonuria – Typical and Atypical
  • Threonine
    • Hyperthreoninaemia
  • Tryptophan
    • Tryptophanuria
  • Valine
    • Hypervalinaemia
  • Histidine
    • Histidinaemia

We will take a detailed look at each in the upcoming posts, so check back often. Essential Amino Acid Metabolic disorders are a serious health problem and must be treated. If a metablic disorder is suspected, it is best to consult a physician.

For more advice on essential amino acids, consult your local expert, Herbal Diet.

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